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Professor and Director
Genetics, Cell Biology and Development
Plant genome engineering through homologous recombination; Retrotransposable elements and genome organization
Selected Recent Publications
- Brady, TL, PG Fuerst, RA Dick, C Schmidt and DF Voytas. Retrotransposon target site selection by imitation of a cellular protein. Mol. Cell. Biol. 2008. 28(4):1230-9.
- Gao, X, H Yi, H Ebina, H Levin and DF Voytas. Chromodomains direct integration of retrotransposons to heterochromatin. Genome Res. 2008. 18(3):359-69.
- Dai J, Xie W, Brady TL, Voytas DF. Phosphorylation regulates integration of the yeast Ty5 retrotransposon into heterochromatin. Mol. Cell. 27:289-299.
- Sander JD, Zaback P, Keith Joung J, Voytas, DF, Dobbs D. ZiFiT: Zinc Finger Targeter: a modular zinc finger/target site design tool. Nucleic Acids Res. 2007 35:W599-605.
- Wright DA, Thibodeau-Beganny S, Sander J, Winfrey RJ, Hirsh AS, Eichtinger,M, Fu F, Porteus MH, Dobbs D, Voytas DF and Joung JK. Standardized reagents and protocols for engineering zinc finger nucleases by modular design. Nature Protocols. 2006 1:1637-1652.
- Gao X, Voytas DF. A eukaryotic gene family related to retroelement integrases. Trends Genet. 2005 21:133-137.
- Gao X, Vander Velden K, Voytas DF, Gu, X. SplitTester: software to identify domains responsible for functional divergence in protein families. BMC Bioinformatics. 2005 6:137.
- Havecker ER, Gao X,Voytas DF. The Sireviruses, a plant-specific lineage of the Ty1/copia retrotranposons, interact with a family of proteins to dynein light chain 8. Plant Physiol. 2005 139:857-868.
- Wright DA, Townsend JA, Winfrey RJ Jr, Irwin PA, Rajagopal J, Lonosky PM, Hall BD, Jondle MD, Voytas DF. High frequency homologous recombination in plants mediated by zinc-finger nucleases. Plant J. 2005 44:693-705.
- Peterson-Burch BD, Nettleton D, Voytas DF. Genomic neighborhoods for Arabidopsis retrotransposons: a role for targeted integration in the distribution of the Metaviridae. Genome Biol. 2004 5:R78.
- Fuerst PG, Voytas DF. CEN plasmid segregation is destabilized by tethered determinants of Ty5 integration specificity: a role for double-strand breaks in CEN antagonism. Chromosoma. 2003 112:58-65.
- Gao X, Havecker ER, Baranov PV, Atkins JF, Voytas DF. Translational recoding signals between gag and pol in diverse LTR retrotransposons. RNA 2003 9:1430-1422.
- Havecker ER, Voytas DF. The soybean retroelement SIRE1 uses stop codon suppression to express its envelope-like protein. EMBO Rep. 2003 4:274-277.
- Laten HM, Havecker ER, Farmer LM, Voytas DF. SIRE1, an endogenous retrovirus family from Glycine max, is highly homogeneous and evolutionarily young. Mol Biol Evol. 2003 20:1222-1230.
- Zhu Y, Dai J, Fuerst, PG, Voytas DF. Controlling integration specificity of a yeast retrotransposon. Proc Natl Acad Sci USA. 2003 100:5891-5895.
- Gao X, Rowley DJ, Gai X, Voytas DF. Ty5 gag mutations increase retrotransposition and suggest a role for hydrogen bonding in the function of the nucleocapsid zinc finger. J. Virol. 2002 76:3240-3247.
- Peterson-Burch B, Voytas DF. Genes of the Pseudoviridae (Ty1/copia retrotransposons). Mol. Biol. Evol. 2002 19:1832-1845.
- Vigdal TJ, Kaufman CD, Izsvak Z, Voytas DF, Ivics Z. Common physical properties of DNA affecting target site selection of Sleeping Beauty and other Tc1/mariner transposable elements. J. Mol. Biol. 2002 323:441-452.
- Wright DA, Voytas DF. Athila4 of Arabidopsis and Calypso of soybean define a lineage of endogenous plant retroviruses. Genome Res. 2002 12:122-131.
- Irwin PA, Voytas DF. Expression and processing of proteins encoded by the Ty5 retrotransposon of Saccharomyces. J. Virol. 2001 75:1790-1797.
- Xie W, Gai X, Zhu Y, Zappulla D, Sternglanz R, Voytas DF. Targeting of the retrotransposon Ty5 to silent chromatin is mediated by interactions between integrase and Sir4p. Mol. Cell. Biol. 2001 21:6601-6614.
Featured News & Events
'Wisc-e-sota', a Joint UMN-UW Virology Training Grant Symposium was first held on Friday, Sepbember 20th, 2013 at the Uniiversity of Wisconsin-La Crosse, Cartwright Center. This was the inaugural collaborative symposium of the NIH T32-supported virology training programs at the University of Wisconsin-Madison and the University of Minnesota-Twin Cities. Talks and poster sessions were presented by students, postdocs and faculty. The second UMN-UW Virology Training Grant Symposium will be held in the Fall 2014. Details to follow.
The 2014 IMV Symposium will be held on May 12, 2014 and Mark Denison (Vanderbilt) and Bert Semler (UC-Irvine) will be the Keynote Speakers. Click on the link below to register and submit abstracts.
Read about bacteriophage phi 29 and why it matters.
Explore nearly a century's worth of discovery in the field of virology at the University of Minnesota.
"This Week in Virology"
from professor Vincent Racaniello.