Research

submenu

Areas of virus research currently being pursued by IMV investigators at the University of Minnesota. This research includes studies of HIV, AIDS research, Herpes virus, Avian flu (Bird flu), Pandemic flu, SARS and West Nile virus.

Antiviral drugs and drug resistance

Antiviral drugs and drug resistance

The study of virus replication for the identification of antiviral drug targets; discovery of small molecules that interfere with virus replication; identification of mutations that confer resistance to antiviral drugs.

Experts include:

Emerging viruses

Emerging viruses

The study of virus transmission and subsequent adaptation to replicate in a new host, with the potential to cause life-threatening disease.

Experts include:

Herpes

Herpes

The study of herpesviruses, including herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV).

Experts include:

HIV/AIDS, retroviruses, pararetroviruses

HIV/AIDS, retroviruses, pararetroviruses

The study of retroviruses, including human immunodeficiency virus (HIV, the etiological agent of AIDS), human T-cell leukemia virus (HTLV), and caulimoviruses.

Experts include:

Host restriction factors and innate immunity

Host restriction factors and innate immunity

The study of evolutionarily conserved cellular proteins that are elicited by viral invasion and restrict viral replication.

Experts include:

 

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

An arterivirus that causes an economically important, panzootic disease that causes reproductive failure in breeding stock and respiratory tract illness in young pigs.

Experts include:

Prions

Prions

Technically not a virus, prions are infectious agents composed of protein in a misfolded form (e.g., scrapie, PrPsc).

Experts include:

 

Vaccines and vaccine development

Vaccines and vaccine development

The development and use of viruses (live or attenuated) for use in boosting immunity to a particular virus for the purpose of preventing disease.

Experts include:

 

Viral immunology

Viral immunology

The study of the host immune response to virus infection.

Experts include:

Viral oncology

Viral oncology

The study of cancer-causing viruses, including HTLV, hepatitis C virus (HCV), hepatitis B virus (HBV), human papilloma virus (HPV), and EBV.

Experts include:

Viral vectors and gene therapy

Viral vectors and gene therapy

The study of viruses for their application as tools to study molecular and/or cellular processes and their use for delivering therapeutic genes for preventing or treating disease.

Experts include:

 

Virus evolution, informatics, and epidemiology

Virus evolution, informatics, and epidemiology

The study of the evolution of viruses, the tracking of virus movement among host populations, and the application of bioinformatics tools towards the study of virus population diversity.

Experts include:

 

Virus-host cell interactions

Virus-host cell interactions

The broad study of the molecular and cellular interactions between virus proteins and/or nucleic acids with cellular proteins and/or nucleic acids that influence the ability of virus to replicate in a cell spread to other cells or hosts.

Experts include:

Virus pathogenesis

Virus pathogenesis

The study of the pathogenic determinants of viruses that enable them to cause disease.

Experts include:

 

Virus replication

Virus replication

The study of the detailed molecular mechanisms that are responsible for the replication of viruses.

Experts include:

 

Virus structure

Virus structure

The study of the structural and biophysical nature of viruses.

Experts include: