Timothy Schacker

Associate Professor

Department of Medicine, Medical School

Email: schac008@umn.edu
Phone: (612) 624-9955

Education

M.D., University of Minnesota, 1986

Research Interests

Dr. Schacker has developed a translational research program focused on HIV transmission and pathogenesis. Areas of interest include factors that increase the likelihood and efficiency of HIV transmission and T cell homeostasis in HIV-1 infected persons.

Selected Recent Publications

• Schacker, TW, Nguyen, PL, Beilman, GJ, Wolinsky, S., Larson, M., Reilly, C., Haase, AT. Collagen deposition in HIV-1 infected lymphatic tissues and T-cell homeostasis. Journal of Clinical Investigation; 110:1133-1139.
• Schacker, T, Nguyen, P, Gatell, J., Reilly, C., Martinez, E., Horban, A., Bakawska, E., Leeuwen, R., Wolinsky, S., Haase, A., Murphy, R., Persistent Abnormalities in Lymphoid Tissues of HIV-Infected Persons Successfully Treated With Anti-Retroviral Therapy. J Infect Dis 2002; 186:1042-7.
• Schacker T, Little S, Connick E, Gebhard K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Schooley RT, Richman D, Corey L, Haase AT. Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection. J Infect Dis 2001; 183:555-62.
• Schacker T, Little S, Connick E, Gebhard-Mitchell K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Richman D, Corey L, Haase AT. Rapid accumulation of human immunodeficiency virus (HIV) in lymphatic tissue reservoirs during acute and early HIV infection: implications for timing of antiretroviral therapy. J Infect Dis 2000; 181:354-7.
• Schacker T, Ryncarz AJ, Goddard J, Diem K, Shaughnessy M, Corey L. Frequent recovery of HIV-1 from genital herpes simplex virus lesions in HIV-1-infected men. Jama 1998; 280:61-6.
• Schacker TW, Hughes JP, Shea T, Coombs RW, Corey L. Biological and virologic characteristics of primary HIV infection. Ann Intern Med 1998; 128:613-20.
• Haase AT, Schacker TW. Potential for the transmission of HIV-1 despite highly active antiretroviral therapy. N Engl J Med 1998; 339:1846-8.
• Schacker T, Collier AC, Hughes J, Shea T, Corey L. Clinical and epidemiologic features of primary HIV infection. Ann Intern Med 1996; 125:257-64.
• Schacker T, Coombs RW, Collier AC, Zeh JE, Fox I, Alam J, Nelson K, Eggert E, Corey L. The effects of high-dose recombinant soluble CD4 on human immunodeficiency virus type 1 viremia. J Infect Dis 1994; 169:37-40.