Wen Sheng

Senior Research Associate

Department of Medicine, Medical School

Email: sheng008@umn.edu
Phone: (612) 824-8517

Education

Ph.D., Virginia Polytechnic Institute and State University

Research Interests

Dr. Sheng is involved in studies of gene expression of primary brain cell cultures exposed to drugs, cytokines/chemokines and human viruses/viral proteins.

Selected Recent Publications

• Sheng WS, Hu S, Lokensgard JR, Peterson PK. U50,488 inhibits HIV-1 Tat-induced monocyte chemoattractant protein-1 (CCL2) production by human astrocytes. Biochem Pharmacol. 2003; 65(1):9-14.
• Hu S, Sheng WS, Lokensgard JR, Peterson PK. Morphine induces apoptosis of human microglia and neurons. Neuropharmacology 2002; 42(6):829-36.
• Lokensgard JR, Hu S, Sheng WS, vanOijen M, Cox D, Cheeran MC, Peterson PK. Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus. J Neurovirol 2001;7:208-219.